Ankle botulinum toxin injections for the treatment of Raynaud’s disease

Published Date: 18th September 2026

Publication Authors: Wyman. M, Lynch. J, Hassan. S, Hassan Z, McArthur. P

Botulinum toxin-A (Btx-A) injections are an established treatment for refractory Raynaud’s disease of the upper limb.1,2 By contrast, relatively little has been written on the use of Btx-A for treatment of Raynaud’s disease of the lower extremity.

Wyman, M; Lynch, J; Hassan, S; Hassan, Z; McArthur. P. (2026). Ankle botulinum toxin injections for the treatment of Raynaud’s disease. JPRAS. 122, pp.251-253. [Online]. Available at: https://doi.org/10.1016/j.bjps.2026.09.027 [Accessed 14 October 2026]