In adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution associated with improved patient-oriented outcomes?

Published Date: 09th June 2026

Publication Authors: Davie. C

A short systematic review was undertaken to answer the following three-part question: in adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution (HAS) associated with improved patient-oriented outcomes? A systematic keyword search of EMBASE, MEDLINE, Cochrane and Google Scholar databases returned three relevant papers which were subsequently used in the final analysis. The author, year, country of publication, patient group studied, study type, key findings and study weaknesses are tabulated. The results suggest that resuscitation with HAS is not recommended in the emergency department in suspected sepsis and larger studies are required to address this clinical question.

Phelan, H.; Davie, C. (2026). In adult patients with suspected sepsis, is adjunct resuscitation with human albumin solution associated with improved patient-oriented outcomes? Emergency Medicine Journal. Online First (09 June 2026), [Online]. Available at: 10.1136/emermed-2026-216135 [Accessed 17 June 2026].