Specialised invasive techniques for cancer-related pain

Published Date: 19th March 2026

Publication Authors: Kalaiyarasan. R

By reading this article, you should be able to:

• Develop a basic understanding of specialised invasive and non-invasive techniques used for complex cancer-related pain. 
• Explain the indications and principles behind advanced procedures such as intrathecal drug delivery devices, cordotomy, dorsal root entry zone (DREZ) lesioning, myelotomy, thalamotomy and cingulotomy. 
• Discuss the emerging role of advanced treatment options including non-invasive and invasive neuromodulation techniques and high-intensity focused ultrasound. 
• Describe how specialised pain management procedures fit within broader oncology and palliative care pathways.

Kalaiyarasan, R. et al. (2026). Specialised invasive techniques for cancer-related pain. BJA Education. 26(5), pp.206-211. [Online]. Available at: https://doi.org/10.1016/j.bjae.2026.02.003 [Accessed 13 April 2026].